Screen many organisms in one assay.
Combine organism-specific targets, antimicrobial resistance markers, and controls on compact ATOM™ chip formats built for high-throughput workflows.
Pathogen detection, sequencing, and surveillance
VirusHunter™ and Pathogen Genomics
VirusHunter demonstrated two complementary uses of programmable DNA chips: detecting many pathogen targets in parallel and reading viral genomes for surveillance. We are building on that foundation for new pathogen genomics collaborations.
A platform proven during the pandemic
Detect the pathogen. Read the genome. Follow change over time.
During the COVID-19 pandemic, Centrillion developed VirusHunter™ assays, ATOM™ chips, and QuadCore™ chips for rapid multiplex detection, SARS-CoV-2 whole-genome sequencing, and variant tracking. The work showed how one programmable DNA chip foundation could support both focused detection and genome-level surveillance.
The historical VirusHunter Multiplex Virus Panel used compact 1 mm × 1 mm ATOM™ chips to organize pathogen targets, antimicrobial resistance markers, and controls in high-throughput plate formats. The VirusHunter ARTIC workflow used tiled QuadCore™ arrays to read SARS-CoV-2 genomes and generate sequence and variant outputs without a conventional sequencing library workflow.
Centrillion is now revisiting this platform for broader pathogen genomics. Potential programs include respiratory or emerging-pathogen panels, resistance surveillance, viral genome monitoring, and custom content designed around a public health, research, or product need.
Resolve genome changes with tiled probes.
Use tiled probe content to reconstruct viral genomes and produce evidence for variant surveillance and genomic epidemiology.
Change the content as the threat changes.
Redesign pathogen targets, resistance markers, controls, and tiled genome content without changing the underlying wafer-scale manufacturing platform.
Discuss this technology